The Selectfluor® reagent family is a series of N-F type electrophilic fluorinating compounds for use in pharmaceutical and agricultural applications. The family includes Selectfluor I and Selectfluor II reagents. Both are versatile, safe and easy-to-use reagents that fluorinate specific positions in complex molecules. Selectfluor reagent rapidly fluorinates a wide range of organic molecules under mild conditions with high efficiency and selectivity. In many cases, Selectfluor reagent can replace toxic or explosive fluorinating reagents such as FClO3 or CF3OF. Selectfluor reagents offer a convenient, less complicated alternative to your fluorination process.
The pharmaceutical and agricultural industries have experimented with and in limited cases, used various fluorinating reagents, including N-F type electrophilic reagents. Many of them, however, have serious limitations. Some have proven to be very costly and difficult to manufacture and are not commercially viable. Other fluorinating reagents tried have lacked sufficient fluorinating efficiency to make a cost-effective impact on chemical synthesis, or have created impurities that required additional manufacturing steps to remove the impurities from the process.
Selectfluor reagents helps to solve all of these problems. Selectfluor reagents are packaged in convenient quantities for R&D evaluation and commercial manufacturing.